Search results for " structures"

showing 10 items of 4162 documents

Bords d'une surface médiane : Identifications et applications

2014

National audience; Un squelette d'une forme fermée est une structure mince, centrée dans cette forme, décrivant sa topologie et sa géométrie. Les squelettes permettent de développer des applications interactives en synthèse d'images~: l'utilisateur peut manipuler intuitivement des formes en modifiant leurs squelettes. Parmi toutes les formulations de squelettes, nous nous intéressons en particulier à la surface médiane. Ses éléments, nommés atomes, sont les sphères maximales intérieures à la forme décrite. Les positions des atomes sont organisées en courbes et surfaces, qui composent la structure squelettale. Cette structure peut être d'une grande aide pour manipuler une forme. Cependant, e…

[ INFO.INFO-MO ] Computer Science [cs]/Modeling and Simulation[INFO.INFO-CG] Computer Science [cs]/Computational Geometry [cs.CG][INFO.INFO-DS]Computer Science [cs]/Data Structures and Algorithms [cs.DS][ INFO.INFO-CG ] Computer Science [cs]/Computational Geometry [cs.CG][INFO.INFO-DS] Computer Science [cs]/Data Structures and Algorithms [cs.DS][INFO.INFO-MO] Computer Science [cs]/Modeling and Simulation[INFO.INFO-CG]Computer Science [cs]/Computational Geometry [cs.CG][INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation[ INFO.INFO-DS ] Computer Science [cs]/Data Structures and Algorithms [cs.DS]
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Efectos teratogenos de la radiacion sobre las extremidades : estudio experimental en el embrion de pollo

1987

Experimental development limbs anormality in the chick embryo by Co-60 radiation is reported along a period of time from hatching until ten days after birth. The malformations in the lower limbs and in the wings are described according to the embriological stage ant the radiation dose used.

animal structuresUNESCO::CIENCIAS MÉDICASembryonic structures:CIENCIAS MÉDICAS [UNESCO]
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Centrioles Shape ERK Signaling Outcomes to Support Lung Branching

2021

Centrioles comprise the heart of centrosomes, where they organize microtubules. To study the function of centrioles in development, we genetically disrupted centrioles throughout the mouse endoderm. Surprisingly, removing centrioles from endoderm did not disrupt intestinal growth or development. In contrast, in the lung, loss of centrioles blocked branching. In lung, loss of centrioles led to apoptosis specifically of SOX2-expressing airway epithelial cells. Loss of centrioles also activated p53. Deleting p53 in mice with acentriolar endoderm rescued SOX2+ cell survival, lung branching and viability. To investigate why endoderm-wide p53 activation specifically disrupted SOX2+ cell survival,…

MAPK/ERK pathwaymedicine.anatomical_structureLungSOX2CentrioleCentrosomeApoptosisMicrotubuleembryonic structuresmedicineEndodermBiologyCell biologySSRN Electronic Journal
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Elektrophysiologische Untersuchung zum Einsatz von Streptolysin O und Natrium-Hyaluronat zur Permeabilitätsmodulation der Membran des runden Fensters…

2003

Background: The round window membrane (RWM) acts like a barrier for topically applied substances into the middle ear preventing diffusion into the perilymphatic fluid compartment. Material and Method: In an animal model, modulation of the permeability of the RWM was attempted using Streptolysin-O (SLO) in various concentrations and sodium hyaluronate. Thereafter, the effect of intratympanically applied Lidocain 2% on hearing threshold measured by auditory brainstem response was tested for Lidocain 2 % and Lidocain 2 % in combination with SLO or sodium hyaluronate. Results: The results show that both, SLO and sodium hyaluronate, influence the effect of Lidocain 2 % on hearing thresholds as a…

Absolute threshold of hearingRound windowgenetic structuresChemistrySodium hyaluronateFluid compartmentsAnatomyPharmacologychemistry.chemical_compoundmedicine.anatomical_structureOtorhinolaryngologyPermeability (electromagnetism)Middle earmedicineStreptolysinsense organsAuditory thresholdsLaryngo-Rhino-Otologie
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Tenascin in denervated human muscle

1996

Tenascin is a large oligomeric glycoprotein of the extracellular matrix. Its location is limited in innervated muscle tissues. We investigated immunohistologically, using two monoclonal antibodies (mab) against Tenascin, biopsied denervated human muscle of children and adults. Tenascin was present in the interstitial space among denervated muscle fibres. Accumulation of Tenascin in denervated adult muscle tissue was frequent, accumulation in denervated muscle tissue of children was sparse and weak. The two antibodies reacted correspondingly. Tenascin was not only found in the vicinity of atrophic muscle fibres, but also close to normally sized fibres, suggesting an early stage of denervatio…

chemistry.chemical_classificationMuscle tissueDenervationendocrine systemPathologymedicine.medical_specialtyanimal structuresbiologymedicine.drug_classTenascinmusculoskeletal systemMonoclonal antibodyExtracellular matrixmedicine.anatomical_structureNeurologychemistryInterstitial spaceembryonic structuresmedicinebiology.proteinImmunohistochemistryNeurology (clinical)GlycoproteinJournal of the Neurological Sciences
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Gender differences in implicit and explicit anxiety measures

2004

Abstract Explicit measures assess introspectively accessible self-descriptions and evaluations. In contrast, implicit measures assess introspectively inaccessible processes that operate outside of awareness. While women consistently yield higher scores on explicit anxiety measures, there are to date no studies available that examine gender differences in implicit anxiety measures. To analyse this topic, we used the Implicit Association Test (Study 1, N =248) and the Emotional Stroop task (Study 2, N =121) as implicit anxiety measures and a standard trait questionnaire as explicit anxiety measure. As expected, women scored higher on the explicit anxiety test. Women also yielded higher anxiet…

genetic structuresPsychometricsImplicit-association testContrast (statistics)Developmental psychologymedicineTraitAnxiety testAnxietymedicine.symptomPersonality Assessment InventoryPsychologypsychological phenomena and processesGeneral PsychologyStroop effectPersonality and Individual Differences
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Atrophic Forms (Dry AMD)

2009

Atrophic form of “Dry AMD” is defined by areas of RPE atrophy, often resulting from regression of confluent soft drusen.

medicine.medical_specialtyRPE atrophymedicine.anatomical_structuregenetic structuresbusiness.industryOphthalmologyMacular atrophymedicinesense organsSoft drusenOuter nuclear layerbusinesseye diseases
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Cecal trap: CT findings of isolated cecal necrosis

2016

Learning objectives Background Findings and procedure details Conclusion Personal information References

genetic structuresGastrointestinal tractIschaemia / InfarctioneducationAbdomenEmergencyCT cecal necrosisAcuteContrast agent-intravenousSettore MED/36 - Diagnostica Per Immagini E RadioterapiaCT
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Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge

2017

Statins, the 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors, are widely prescribed for treatment of hypercholesterolemia. Although statins are generally well tolerated, up to ten percent of statin-treated patients experience myalgia symptoms, defined as muscle pain without elevated creatinine phosphokinase (CPK) levels. Myalgia is the most frequent reason for discontinuation of statin therapy. The mechanisms underlying statin myalgia are not clearly understood. To elucidate changes in gene expression associated with statin myalgia, we compared profiles of gene expression in skeletal muscle biopsies from patients with statin myalgia who were undergoing statin re-challenge (cases)…

Male0301 basic medicinemyalgiaGene Expressionlcsh:MedicineApoptosis030204 cardiovascular system & hematologyPathology and Laboratory MedicineBioinformaticsBiochemistry0302 clinical medicineMedicine and Health SciencesGene Regulatory Networkslcsh:ScienceMusculoskeletal SystemEnergy-Producing OrganellesMyositisRegulation of gene expressionMultidisciplinaryCell DeathbiologyMusclesDrugsMiddle AgedMitochondriaCell ProcessesHMG-CoA reductaseFemalelipids (amino acids peptides and proteins)AnatomyCellular Structures and Organellesmedicine.symptomResearch ArticleSenescencemedicine.medical_specialtyStatinmedicine.drug_classPainBioenergeticsPolymorphism Single Nucleotide03 medical and health sciencesSigns and SymptomsDiagnostic MedicineInternal medicineGeneticsmedicineHumansGene Regulationcardiovascular diseasesMuscle SkeletalAgedPharmacologybusiness.industrylcsh:RStatinsBiology and Life SciencesComputational Biologynutritional and metabolic diseasesMyalgiaCell Biologymedicine.disease030104 developmental biologyEndocrinologyGene Expression RegulationSkeletal MusclesLeukocytes Mononuclearbiology.proteinProtein prenylationlcsh:QHydroxymethylglutaryl-CoA Reductase InhibitorsSLCO1B1businessPLOS ONE
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Evidence for the mechanosensor function of filamin in tissue development

2016

AbstractCells integrate mechanical properties of their surroundings to form multicellular, three-dimensional tissues of appropriate size and spatial organisation. Actin cytoskeleton-linked proteins such as talin, vinculin and filamin function as mechanosensors in cells, but it has yet to be tested whether the mechanosensitivity is important for their function in intact tissues. Here we tested, how filamin mechanosensing contributes to oogenesis in Drosophila. Mutations that require more or less force to open the mechanosensor region demonstrate that filamin mechanosensitivity is important for the maturation of actin-rich ring canals that are essential for Drosophila egg development. The ope…

MaleTalin0301 basic medicineanimal structuresFilaminsMutantmacromolecular substancesPlasma protein bindingFilaminmedicine.disease_causeArticle03 medical and health sciencesFilamin bindingOogenesismedicineAnimalsActinOvumMutationMultidisciplinarybiologyta1182VinculinActinsVinculin3. Good healthCell biology030104 developmental biologymechanosensor functionMutationddc:000biology.proteinDrosophilaFemaletissue developmentFunction (biology)Protein BindingScientific Reports
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